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Meta
Steroids can aid pneumonia treatment
19/01/10
Steroids can prove to be an effective option with antibiotics when it comes to reducing recovery time associated with pneumonia, according to a study by researchers from the UT Southwestern Medical Center.
The study suggested that health of a patient suffering from pneumonia can be restored easily if steroids are administered in a combination with antibiotics as compared to the use of antibiotics alone.
From News-medical.net:
Adding corticosteroids to traditional antimicrobial therapy might help people with pneumonia recover more quickly than with antibiotics alone, UT Southwestern Medical Center scientists have found.
Unlike the anabolic steroids used to bulk up muscle, corticosteroids are often used to treat inflammation related to infectious diseases, such as bacterial meningitis. Used against other infectious diseases, however, steroid therapy has been shown to be ineffective or even harmful.
In a study available online and in a future issue of the Journal of Infectious Diseases, researchers at UT Southwestern show that mice infected with a type of severe bacterial pneumonia and subsequently treated with steroids and antibiotics recovered faster and had far less inflammation in their lungs than mice treated with antibiotics alone.
The study led by Dr. Robert Hardy, Study’s Senior Author & Associate Professor of Internal Medicine and Pediatrics, also suggested that steroids are good for treating inflammation of the lungs while antibiotics prove effective for killing the bug.
The addition to corticosteroids to the traditional antimicrobial therapy can prove to be very effective in treating patients suffering from pneumonia than treating them with antibiotics alone, as per scientists from the UT Southwestern Medical Center.
Pneumonia is an infection of the lung, which is primarily characterized by breathing disorders and is spread by coughing and sneezing.
Dr. Robert Hardy, Associate Professor of Internal Medicine and Pediatrics and the study’s Senior Author remarked that steroids can prove their real worth when it comes to restoration of health after an individual catches pneumonia.
From News-Medical.Net:
In the current study, mice infected with the M pneumoniae bacterium were treated daily with a placebo, an antibiotic, a steroid, or a combination of the antibiotic and steroid in order to investigate the effect on M pneumoniae-induced airway inflammation. The animals were then evaluated after one, three and six days of therapy.
“It turns out that the group that got both the antibiotic and the steroids did the best,” Dr. Hardy said. “The inflammation in their lungs got significantly better.”
Although antimicrobials remain the primary therapy for M pneumoniae infection, there have been several reports in recent years about physicians adding steroids to the treatment regimen of patients with severe cases, Dr. Hardy said. The problem, he said, is that those were individual case reports.
“They never had a control group, so it was impossible to tell what impact the addition of steroids had on recovery,” he said.
It was also remarked by Dr. Hardy that though it is too early for him or others to recommend steroids as a form of standard treatment to patients with bacterial pneumonia but the findings do support the need for a clinical trial in the near future.